Clinical and Microbiological Evaluation of the Effect of Heat Killed Lactobacillus Acidophilus and Garlic Extract on Candida Albicans in a Group of Elderly Denture Wearers

Continuous denture wearing, lack of adequate hygiene and infection with Candida albicans (C. albicans) are among the etiological factors Denture stomatitis (DS). The management DS ranges from implementation oral measures removal predisposing to use antifungals, depending on severity inflammation. Aim study: This study aimed evaluate short-term effect heat killed lactobacillus acidophilus - Lacteol Fort® (LF)- as a probiotic garlic extract -Tomex Plus® (TP)- prebiotic salivary C. counts biofilm-forming ability, in elderly wearers DS. Methods: was single-center, single‐blind, randomized pilot clinical trial. 27 complete were randomly allocated into 3 groups; group I (control), II (LF) III (TP). Each clinically assessed for microbiologically evaluated at baseline after 15 days. ability assessed, well, each end experimental period. Results: assessment revealed reduction total erythematous area dimension 3.00 ± 0.40 mm 3.20 0.54 (TP) ≤2 either treatment. Microbiological evaluation showed that significantly lowered groups Conclusion: LF TP both found be effective reducing associated inflammation, ability.